Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9949467 | 0.86 | TSHR (0.55) | MAPTTSHRL3MBTL1AKR1C3ALDH1A1 | |
| SCHEMBL9949471 | 0.86 | TSHR (0.55) | MAPTTSHRL3MBTL1AKR1C3ALDH1A1 | |
| SCHEMBL1439777 | 0.81 | TSHR (0.64) | MAPTTSHRL3MBTL1AKR1C3ALDH1A1 | |
| SCHEMBL9949602 | 0.81 | TSHR (0.64) | MAPTTSHRL3MBTL1AKR1C3ALDH1A1 | |
| SCHEMBL9949812 | 0.81 | TSHR (0.64) | MAPTTSHRL3MBTL1AKR1C3ALDH1A1 | |
| SCHEMBL10179066 | 0.81 | CYP1A2 (0.65) | TSHRALDH1A1KMT2ACYP1A2 | |
| SCHEMBL9949804 | 0.81 | CYP1A2 (0.65) | TSHRALDH1A1KMT2ACYP1A2 | |
| SCHEMBL16051363 | 0.79 | MAPT (0.55) | MAPTTSHRL3MBTL1AKR1C3ALDH1A1 | |
| SCHEMBL2891211 | 0.78 | CYP1A2 (0.55) | TSHRALDH1A1KMT2ACYP1A2 | |
| SCHEMBL26733039 | 0.78 | KMT2A (0.49) | MAPTTSHRKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2212297-A1 | INHIBITORS OF PROTEIN KINASES | Ingenium Pharmaceuticals GmbH (DE) | 2010-08-04 | — | — | EP | disclosed |
| WO-2009047359-A1 | INHIBITORS OF PROTEIN KINASES | INGENIUM PHARMACEUTICALS GMBH (DE) | 2009-04-16 | — | — | WO | disclosed |