Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA9 | Q16790 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3853544 | 1.00 | MEN1 (0.56) | MEN1PABPC1KMT2ACA12CA1 | |
| SCHEMBL29093251 | 1.00 | MEN1 (0.56) | MEN1PABPC1KMT2ACA12CA1 | |
| SCHEMBL3855876 | 1.00 | MEN1 (0.56) | MEN1PABPC1KMT2ACA12CA1 | |
| SCHEMBL28688739 | 1.00 | MEN1 (0.56) | MEN1PABPC1KMT2ACA12CA1 | |
| SCHEMBL3856268 | 1.00 | MEN1 (0.56) | MEN1PABPC1KMT2ACA12CA1 | |
| SCHEMBL3856237 | 0.99 | MEN1 (0.57) | MEN1PABPC1KMT2ACA12CA1 | |
| SCHEMBL3851646 | 0.95 | MEN1 (0.59) | MEN1PABPC1KMT2ACA12CA1 | |
| SCHEMBL3854103 | 0.90 | MEN1 (0.61) | MEN1PABPC1KMT2ACA12CA1 | |
| SCHEMBL3860588 | 0.86 | MEN1 (0.51) | MEN1PABPC1KMT2ACA12CA1 | |
| SCHEMBL3861517 | 0.86 | MEN1 (0.51) | MEN1PABPC1KMT2ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260107-B | Antitumor prodrug, pharmaceutical composition and application thereof in tumor targeted therapy field | 烟台邦杰生物科技有限公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-116947765-A | Antitumor prodrug, pharmaceutical composition and application thereof in tumor targeted therapy field | 烟台邦杰生物科技有限公司 | 2023-10-27 | — | — | CN | disclosed |