Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 19/20 | 0.62 |
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29093537 | 1.00 | TLR8 (0.62) | TLR8TLR7 | |
| SCHEMBL29093522 | 0.87 | TLR8 (0.64) | TLR8TLR7 | |
| SCHEMBL29093527 | 0.87 | TLR8 (0.64) | TLR8TLR7 | |
| SCHEMBL29093496 | 0.85 | TLR8 (0.65) | TLR8TLR7 | |
| SCHEMBL29093504 | 0.85 | TLR8 (0.65) | TLR8TLR7 | |
| SCHEMBL30557815 | 0.85 | TLR8 (0.65) | TLR8TLR7 | |
| SCHEMBL18125210 | 0.84 | TLR8 (0.74) | TLR8TLR7 | |
| SCHEMBL18125191 | 0.84 | TLR8 (0.74) | TLR8TLR7 | |
| SCHEMBL29093659 | 0.83 | TLR8 (0.62) | TLR8TLR7 | |
| SCHEMBL29093658 | 0.83 | TLR8 (0.62) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116768883-A | Pyrimido aromatic ring compounds and application thereof in medicines | 广东东阳光药业股份有限公司 | 2023-09-19 | — | — | CN | disclosed |