Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29631652 | 1.00 | TSHR (0.37) | TSHRPOLBLMNARAB9AMAPT | |
| SCHEMBL7380748 | 0.83 | F10 (0.37) | POLBLMNAKMT2AMEN1GAA | |
| SCHEMBL24565349 | 0.80 | F10 (0.39) | POLBLMNAMAPTKMT2AMEN1 | |
| SCHEMBL7328219 | 0.80 | F10 (0.39) | POLBLMNAMAPTKMT2AMEN1 | |
| SCHEMBL24565293 | 0.79 | F10 (0.38) | TSHRPOLBLMNAMAPTKMT2A | |
| SCHEMBL24565300 | 0.78 | CYP3A4 (0.38) | TSHRPOLBLMNAMAPTKMT2A | |
| SCHEMBL19419830 | 0.78 | CYP3A4 (0.38) | TSHRPOLBLMNAMAPTKMT2A | |
| SCHEMBL29631654 | 0.76 | MEN1 (0.31) | TSHRRAB9AMAPTKMT2AMEN1 | |
| SCHEMBL27221189 | 0.76 | MEN1 (0.31) | TSHRRAB9AMAPTKMT2AMEN1 | |
| SCHEMBL8198244 | 0.74 | TSHR (0.44) | TSHRPOLBLMNARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116528869-A | Amino heteroaryl kinase inhibitors | 安锐生物医药科技(广州)有限公司 | 2023-08-01 | — | — | CN | disclosed |