Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKZF2 | Q9UKS7 | 5/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 14/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 14/20 | 0.41 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.37 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | IL1B | P01584 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30702784 | 1.00 | IKZF2 (0.43) | IKZF2DDB1CRBNIKZF3IKZF1 | |
| SCHEMBL24821058 | 0.80 | TLR9 (0.46) | IKZF2IKZF1 | |
| Hydrochloric Acid SCHEMBL29094577 | 0.79 | TLR9 (0.45) | IKZF2IKZF1 | |
| Hydrochloric Acid SCHEMBL30702808 | 0.79 | TLR9 (0.45) | IKZF2IKZF1 | |
| SCHEMBL23540197 | 0.77 | DDB1 (0.55) | IKZF2DDB1CRBNIKZF3IKZF1 | |
| SCHEMBL29079566 | 0.76 | CRBN (0.50) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL29767993 | 0.76 | CRBN (0.50) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL30574620 | 0.75 | CRBN (0.43) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL29079653 | 0.75 | CRBN (0.43) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL29079651 | 0.74 | CRBN (0.43) | IKZF2DDB1CRBNIKZF3TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116891502-A | EGFR degrading agent | 上海齐鲁制药研究中心有限公司 | 2023-10-17 | — | — | CN | disclosed |