Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 9/20 | 0.67 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.62 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.62 |
| ▸ | BRD4 | O60885 | 1/20 | 0.62 |
| ▸ | TNF | P01375 | 1/20 | 0.62 |
| ▸ | IL1B | P01584 | 1/20 | 0.62 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.62 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.57 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.53 |
| ▸ | MAP1LC3B | Q9GZQ8 | 11/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29094720 | 0.90 | CRBN (0.62) | CRBNIKZF3IKZF1BRD4TNF | |
| SCHEMBL29094750 | 0.89 | CRBN (0.64) | CRBNIKZF3IKZF1BRD4TNF | |
| SCHEMBL30992940 | 0.89 | CRBN (0.65) | CRBNIKZF3IKZF1BRD4TNF | |
| SCHEMBL30713738 | 0.88 | CRBN (0.51) | CRBNIKZF3IKZF1BRD4TNF | |
| SCHEMBL29094761 | 0.88 | CRBN (0.51) | CRBNIKZF3IKZF1BRD4TNF | |
| SCHEMBL30993083 | 0.88 | CRBN (0.63) | CRBNIKZF3IKZF1BRD4TNF | |
| SCHEMBL24816666 | 0.86 | CRBN (0.62) | CRBNIKZF3IKZF1BRD4TNF | |
| SCHEMBL20260446 | 0.85 | CRBN (0.67) | CRBNIKZF3IKZF1BRD4TNF | |
| SCHEMBL24967103 | 0.84 | CRBN (0.72) | CRBNIKZF3IKZF1BRD4TNF | |
| SCHEMBL30993059 | 0.83 | CRBN (0.64) | CRBNIKZF3IKZF1BRD4TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116940581-A | Novel protein degradation agent and application thereof | 和径医药科技（上海）有限公司 | 2023-10-24 | — | — | CN | disclosed |