Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 18/20 | 0.42 |
| ▸ | JAK1 | P23458 | 17/20 | 0.42 |
| ▸ | TYK2 | P29597 | 7/20 | 0.42 |
| ▸ | JAK3 | P52333 | 7/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29958824 | 1.00 | JAK2 (0.42) | JAK2JAK1TYK2JAK3LRRK2 | |
| SCHEMBL31144194 | 0.92 | JAK2 (0.38) | JAK2JAK1TYK2JAK3LRRK2 | |
| SCHEMBL27028643 | 0.92 | JAK2 (0.43) | JAK2JAK1TYK2JAK3LRRK2 | |
| SCHEMBL27028659 | 0.90 | IRAK4 (0.46) | JAK2JAK1TYK2JAK3LRRK2 | |
| SCHEMBL29958828 | 0.90 | IRAK4 (0.46) | JAK2JAK1TYK2JAK3LRRK2 | |
| SCHEMBL27028649 | 0.89 | JAK2 (0.38) | JAK2JAK1TYK2JAK3LRRK2 | |
| SCHEMBL27028581 | 0.88 | JAK2 (0.44) | JAK2JAK1TYK2JAK3LRRK2 | |
| SCHEMBL31144211 | 0.87 | JAK2 (0.40) | JAK2JAK1TYK2JAK3LRRK2 | |
| SCHEMBL27028612 | 0.87 | JAK2 (0.39) | JAK2JAK1TYK2JAK3LRRK2 | |
| SCHEMBL27028734 | 0.86 | JAK2 (0.35) | JAK2JAK1TYK2JAK3LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116981459-A | Heterocyclic derivatives as janus kinase inhibitors | 奇斯药制品公司 | 2023-10-31 | — | — | CN | claimed |