Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL524425 | 0.97 | — | — | |
| Bromide SCHEMBL2470982 | 0.97 | — | — | |
| SCHEMBL233483 | 0.94 | — | — | |
| Bromide SCHEMBL1649333 | 0.89 | — | — | |
| Sulfuric Acid SCHEMBL4408205 | 0.82 | CYP1A2 (0.76) | — | |
| Bromide SCHEMBL17747992 | 0.82 | HRH4 (1.00) | — | |
| Bromide SCHEMBL4434174 | 0.81 | CYP1A2 (0.95) | — | |
| SCHEMBL9197363 | 0.78 | — | — | |
| Bromide SCHEMBL8582620 | 0.77 | HRH4 (0.77) | — | |
| Hydrochloric Acid SCHEMBL31317493 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116554120-B | Preparation method of 2-amino-2-thiazoline | 山东国邦药业有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-116554120-A | Preparation method of 2-amino-2-thiazoline | 山东国邦药业有限公司 | 2023-08-08 | — | — | CN | disclosed |