Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | CD274 | Q9NZQ7 | 18/20 | 0.48 |
| ▸ | PDCD1 | Q15116 | 6/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13117384 | 0.89 | CA12 (0.45) | FFAR1CD274MCL1 | |
| SCHEMBL13139653 | 0.89 | CD274 (0.46) | FFAR1CD274PDCD1 | |
| SCHEMBL12578389 | 0.87 | FFAR1 (0.48) | FFAR1CD274 | |
| SCHEMBL13117681 | 0.86 | CA12 (0.44) | FFAR1CD274PDCD1MCL1 | |
| SCHEMBL12578352 | 0.84 | FFAR1 (0.51) | FFAR1CD274PDCD1 | |
| SCHEMBL3514126 | 0.83 | FFAR1 (0.46) | FFAR1CD274PDCD1MCL1HDAC6 | |
| SCHEMBL12578384 | 0.82 | FFAR1 (0.46) | FFAR1CD274 | |
| SCHEMBL12578387 | 0.82 | FFAR1 (0.46) | FFAR1CD274 | |
| SCHEMBL12578350 | 0.82 | FFAR1 (0.46) | FFAR1CD274 | |
| SCHEMBL2912263 | 0.82 | FFAR1 (0.54) | FFAR1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2216330-A1 | OXADIAZOLIDINEDIONE COMPOUND | Astellas Pharma Inc. (JP) | 2010-08-11 | — | — | EP | disclosed |