Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.42 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29828840 | 1.00 | ATM (0.49) | ATMADORA1TSHRSYKAPP | |
| SCHEMBL29096928 | 1.00 | ATM (0.49) | ATMADORA1TSHRSYKAPP | |
| SCHEMBL30639558 | 0.90 | ATM (0.53) | ATMTSHRSYKAPPCYP3A4 | |
| SCHEMBL29828457 | 0.84 | ATM (0.48) | ATMADORA1TSHRSYKAPP | |
| SCHEMBL29828726 | 0.83 | ATM (0.47) | ATMSYKAPPCYP3A4KLK5 | |
| SCHEMBL29096917 | 0.83 | ATM (0.47) | ATMSYKAPPCYP3A4KLK5 | |
| SCHEMBL29096915 | 0.83 | ATM (0.47) | ATMSYKAPPCYP3A4KLK5 | |
| SCHEMBL30639517 | 0.82 | ATM (0.52) | ATMAPPCYP3A4KLK5CTSS | |
| SCHEMBL27129781 | 0.82 | ATM (0.52) | ATMAPPCYP3A4KLK5CTSS | |
| SCHEMBL27032790 | 0.82 | ATM (0.52) | ATMAPPCYP3A4KLK5CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116981672-A | Macrocyclic compounds as CFTR modulators | 爱杜西亚药品有限公司 | 2023-10-31 | — | — | CN | disclosed |