Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.44 |
| ▸ | APP | P05067 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29097158 | 1.00 | ATM (0.52) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27129781 | 0.92 | ATM (0.52) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL30639517 | 0.92 | ATM (0.52) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27032790 | 0.92 | ATM (0.52) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29828836 | 0.91 | ATM (0.47) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27147982 | 0.87 | ATM (0.55) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27032820 | 0.87 | ATM (0.55) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL30639558 | 0.85 | ATM (0.53) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29828726 | 0.83 | ATM (0.47) | ATMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL29096917 | 0.83 | ATM (0.47) | ATMHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116981672-A | Macrocyclic compounds as CFTR modulators | 爱杜西亚药品有限公司 | 2023-10-31 | — | — | CN | disclosed |