Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.55 |
| ▸ | RXRA | P19793 | 3/20 | 0.50 |
| ▸ | RXRB | P28702 | 3/20 | 0.50 |
| ▸ | RXRG | P48443 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27197550 | 0.93 | HRH3 (0.64) | HRH3RXRARXRBRXRGNPC1 | |
| SCHEMBL29097886 | 0.87 | HRH3 (0.53) | HRH3RXRARXRBRXRGNPC1 | |
| SCHEMBL30199347 | 0.86 | NR1H2 (0.55) | HRH3 | |
| SCHEMBL29098091 | 0.85 | F10 (0.51) | HRH3RXRARXRBRXRGNPC1 | |
| SCHEMBL29097990 | 0.84 | HRH3 (0.50) | HRH3RXRARXRBRXRGNPC1 | |
| SCHEMBL29097893 | 0.84 | S1PR1 (0.53) | HRH3RXRARXRBRXRGNPC1 | |
| SCHEMBL29097927 | 0.84 | MAOB (0.52) | HRH3RXRARXRBRXRGNPC1 | |
| SCHEMBL29098068 | 0.83 | MAOB (0.51) | HRH3RXRARXRBRXRGNPC1 | |
| SCHEMBL24229547 | 0.82 | TMEM97 (0.66) | HRH3HRH1 | |
| SCHEMBL29097908 | 0.82 | NR4A2 (0.53) | HRH3NPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594669-A | Fused ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |