Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 3/20 | 0.44 |
| ▸ | RXRB | P28702 | 3/20 | 0.44 |
| ▸ | RXRG | P48443 | 3/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PREP | P48147 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29098088 | 0.92 | HRH3 (0.53) | HRH3S1PR1CYP4F2CYP4A11RXRA | |
| SCHEMBL29098068 | 0.90 | MAOB (0.51) | HRH3S1PR1MAOBCYP4F2CYP4A11 | |
| SCHEMBL30198885 | 0.86 | ESR2 (0.53) | HRH3S1PR1CYP4F2CYP4A11 | |
| SCHEMBL30199620 | 0.86 | ESR2 (0.53) | HRH3S1PR1CYP4F2CYP4A11 | |
| SCHEMBL29097963 | 0.86 | ESR2 (0.53) | HRH3S1PR1CYP4F2CYP4A11 | |
| SCHEMBL29097811 | 0.85 | HRH3 (0.44) | HRH3S1PR1RXRARXRBRXRG | |
| SCHEMBL29097908 | 0.83 | NR4A2 (0.53) | HRH3MAOBNPC1RAB9A | |
| SCHEMBL27197550 | 0.82 | HRH3 (0.64) | HRH3RXRARXRBRXRGNPC1 | |
| SCHEMBL29097886 | 0.81 | HRH3 (0.53) | HRH3S1PR1MAOBRXRARXRB | |
| SCHEMBL29097927 | 0.81 | MAOB (0.52) | HRH3S1PR1MAOBRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594669-A | Fused ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |