Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466726 | 0.89 | TSHR (0.45) | TSHRCYP3A4 | |
| Triethyl Phosphate SCHEMBL21887 | 0.81 | TSHR (1.00) | TSHRTP53TDP1PPARDCYP3A4 | |
| Triethyl Phosphate SCHEMBL27822049 | 0.81 | TSHR (1.00) | TSHRTP53TDP1PPARDCYP3A4 | |
| Triethyl Phosphate SCHEMBL28023664 | 0.81 | TSHR (1.00) | TSHRTP53TDP1PPARDCYP3A4 | |
| Triethyl Phosphate SCHEMBL1332591 | 0.81 | TSHR (1.00) | TSHRTP53TDP1PPARDCYP3A4 | |
| SCHEMBL4971866 | 0.78 | TSHR (0.71) | TSHRTP53TDP1PPARDMEN1 | |
| Triethyl Phosphate SCHEMBL23092283 | 0.78 | TSHR (0.93) | TSHRTP53TDP1PPARDCYP3A4 | |
| Triethyl Phosphate SCHEMBL1332661 | 0.78 | TSHR (0.93) | TSHRTP53TDP1PPARDCYP3A4 | |
| Triethyl Phosphate SCHEMBL11296643 | 0.78 | TSHR (0.93) | TSHRTP53TDP1PPARDCYP3A4 | |
| Triethyl Phosphate SCHEMBL28610243 | 0.78 | TSHR (0.93) | TSHRTP53TDP1PPARDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116987116-B | Continuous synthesis method of diethyl methylthiomethyl phosphate | 常州合全药业有限公司 | 2023-12-01 | — | — | CN | claimed |
| CN-116987116-A | Continuous synthesis method of diethyl methylthiomethyl phosphate | 常州合全药业有限公司 | 2023-11-03 | — | — | CN | claimed |
| CN-116987116-B | Continuous synthesis method of diethyl methylthiomethyl phosphate | 常州合全药业有限公司 | 2023-12-01 | — | — | CN | disclosed |
| CN-116987116-B | Continuous synthesis method of diethyl methylthiomethyl phosphate | 常州合全药业有限公司 | 2023-12-01 | — | — | CN | disclosed |
| CN-116987116-B | Continuous synthesis method of diethyl methylthiomethyl phosphate | 常州合全药业有限公司 | 2023-12-01 | — | — | CN | disclosed |
| CN-116987116-A | Continuous synthesis method of diethyl methylthiomethyl phosphate | 常州合全药业有限公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-116987116-A | Continuous synthesis method of diethyl methylthiomethyl phosphate | 常州合全药业有限公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-116987116-A | Continuous synthesis method of diethyl methylthiomethyl phosphate | 常州合全药业有限公司 | 2023-11-03 | — | — | CN | disclosed |