Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 14/20 | 0.59 |
| ▸ | PIK3CD | O00329 | 11/20 | 0.59 |
| ▸ | PIK3CB | P42338 | 9/20 | 0.59 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.59 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11938412 | 1.00 | PIK3CA (0.59) | PIK3CAPIK3CDPIK3CBPIK3CGPIK3C2B | |
| SCHEMBL11938414 | 0.78 | HTT (0.54) | PIK3CAPIK3CDPIK3CBPIK3CGPIK3C2B | |
| SCHEMBL32670693 | 0.77 | PIK3CA (0.61) | PIK3CAPIK3CDPIK3CBPIK3CGPIK3C2B | |
| SCHEMBL13030316 | 0.77 | PIK3CA (0.75) | PIK3CAPIK3CDPIK3CBPIK3CGPIK3C2B | |
| SCHEMBL32670771 | 0.76 | PIK3CA (0.79) | PIK3CAPIK3CDPIK3CBPIK3CGPIK3C2B | |
| SCHEMBL3511252 | 0.75 | PIK3CA (0.75) | PIK3CAPIK3CDPIK3CBPIK3CGPIK3C2B | |
| SCHEMBL12700770 | 0.75 | PIK3CA (1.00) | PIK3CAPIK3CDPIK3CBPIK3CGPIK3C2B | |
| SCHEMBL14833311 | 0.75 | PIK3CA (1.00) | PIK3CAPIK3CDPIK3CBPIK3CGPIK3C2B | |
| SCHEMBL31461158 | 0.74 | KDM4E (0.58) | SMN1; SMN2RAB9A | |
| SCHEMBL13030408 | 0.74 | PIK3CA (1.00) | PIK3CAPIK3CDPIK3CBPIK3CGPIK3C2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611883-B | PI3K alpha inhibitor with double-ring structure, and preparation method and application thereof | 生物岛实验室 | 2025-03-28 | — | — | CN | disclosed |
| CN-115611883-A | PI3K alpha inhibitor with bicyclic structure and preparation method and application thereof | 生物岛实验室 | 2023-01-17 | — | — | CN | disclosed |