Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 19/20 | 0.42 |
| ▸ | JAK2 | O60674 | 5/20 | 0.42 |
| ▸ | TYK2 | P29597 | 7/20 | 0.40 |
| ▸ | JAK3 | P52333 | 7/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29100338 | 1.00 | JAK1 (0.42) | JAK1JAK2TYK2JAK3CYP3A4 | |
| SCHEMBL29460614 | 1.00 | JAK1 (0.42) | JAK1JAK2TYK2JAK3CYP3A4 | |
| SCHEMBL30995752 | 0.86 | JAK1 (0.42) | JAK1JAK2TYK2JAK3CYP3A4 | |
| SCHEMBL25699287 | 0.86 | JAK1 (0.42) | JAK1JAK2TYK2JAK3CYP3A4 | |
| SCHEMBL2223896 | 0.86 | JAK1 (0.42) | JAK1JAK2TYK2JAK3CYP3A4 | |
| SCHEMBL25283735 | 0.86 | JAK1 (0.42) | JAK1JAK2TYK2JAK3CYP3A4 | |
| SCHEMBL25241529 | 0.86 | JAK1 (0.42) | JAK1JAK2TYK2JAK3CYP3A4 | |
| SCHEMBL29460490 | 0.86 | JAK1 (0.42) | JAK1JAK2TYK2JAK3CYP3A4 | |
| SCHEMBL2280654 | 0.82 | JAK1 (0.45) | JAK1JAK2TYK2JAK3CYP3A4 | |
| SCHEMBL2224738 | 0.81 | JAK1 (0.46) | JAK1JAK2TYK2JAK3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116925077-A | Pyrido ring compound, and preparation method, intermediate, composition and application thereof | 一又生物(上海)有限公司 | 2023-10-24 | — | — | CN | disclosed |
| CN-114149428-B | Pyrido ring compound, and preparation method, intermediate, composition and application thereof | 中国药科大学 | 2023-06-13 | — | — | CN | disclosed |