SCHEMBL29100706

SCHEMBL29100706

CC(C)(C)OC(=O)CCC(O)C(=O)OC(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
CYP2D6 P10635 1/20 0.37
APP P05067 1/20 0.33
NOS1 P29475 2/20 0.33
NOS3 P29474 1/20 0.33
NOS2 P35228 1/20 0.33
MEN1 O00255 1/20 0.33
GAA P10253 1/20 0.33
KMT2A Q03164 1/20 0.33
TET2 Q6N021 3/20 0.31
KDM4A O75164 2/20 0.31
KDM4C Q9H3R0 2/20 0.31
KDM2A Q9Y2K7 2/20 0.31
TET3 O43151 1/20 0.31
STING1 Q86WV6 1/20 0.31
AAK1 Q2M2I8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29100702 1.00 HDAC3 (0.39) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL9668938 0.89 TSHR (0.43) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL7588140 0.89 CYP2D6 (0.38) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL27008556 0.89 HDAC3 (0.37) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL25406495 0.84 TET2 (0.50) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL17726829 0.84 TET2 (0.50) CYP2D6MEN1GAAKMT2ATET2
SCHEMBL9625892 0.84 TET2 (0.50) CYP2D6MEN1GAAKMT2ATET2
SCHEMBL13765204 0.84 TET2 (0.50) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL29003087 0.84 TET2 (0.50) HDAC3HDAC1HDAC2HDAC8HDAC6
SCHEMBL26272995 0.84 HDAC3 (0.39) HDAC3HDAC1HDAC2HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116981486-A Dual mode radiotracer and therapeutic agent 慕尼黑工业大学 2023-10-31 CN disclosed