Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 6/20 | 1.00 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 3/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29701766 | 1.00 | DAO (1.00) | DAOPRKCIAURKAPARP1AURKB | |
| SCHEMBL29544574 | 0.84 | DAO (0.72) | DAOPRKCIAURKAAURKB | |
| SCHEMBL19876250 | 0.84 | DAO (0.72) | DAOPRKCIAURKAAURKB | |
| SCHEMBL1135576 | 0.76 | DAO (0.61) | DAOAURKAPARP1AURKB | |
| SCHEMBL8483100 | 0.76 | DAO (0.61) | DAOAURKAPARP1 | |
| SCHEMBL9909699 | 0.72 | DAO (0.56) | DAOAURKAPARP1AURKB | |
| SCHEMBL8483308 | 0.69 | DAO (0.53) | DAO | |
| SCHEMBL9909765 | 0.68 | BRAF (0.57) | DAOAURKA | |
| SCHEMBL15566518 | 0.68 | DAO (0.52) | DAO | |
| SCHEMBL30055673 | 0.65 | DAO (0.49) | DAOPRKCIAURKAPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116981667-A | Heterocyclic inhibitors of EGFR and/or HER2 for cancer treatment | 蝎子疗法股份有限公司 | 2023-10-31 | — | — | CN | disclosed |