⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11755694 | 1.00 | — | — | |
| SCHEMBL202877 | 1.00 | — | — | |
| SCHEMBL11755699 | 1.00 | — | — | |
| SCHEMBL202878 | 1.00 | — | — | |
| SCHEMBL9161921 | 0.94 | — | — | |
| SCHEMBL9161917 | 0.94 | — | — | |
| Dioxane SCHEMBL9646498 | 0.85 | HSD17B10 (0.30) | — | |
| Dioxane SCHEMBL9646503 | 0.85 | HSD17B10 (0.30) | — | |
| SCHEMBL6153449 | 0.82 | — | — | |
| SCHEMBL6153448 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060000778-A1 | high-performance membrane designed for the selective removal of a polar fluid (water) from less polar fluids (organic solvents), by a pervaporation using a composite membrane contaiing ultrafiltration membrane as support ( e.g. cellulose acetate) and a crosslinked copolymer of anionic, cationic monomers | MCMASTER UNIVERSITY (CA) | 2006-01-05 | — | — | US | claimed |
| WO-2023122778-A1 | PYRIDAZINONE DERIVATIVES USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |
| US-9562019-B2 | Substituted pyridazines as EGFR and/or KRAS inhibitors | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2017-02-07 | — | — | US | disclosed |
| EP-2518063-B1 | Pyridazinones and furan-containing compounds | SLOAN-KETTERING INST FOR CANCER RES (US) | 2017-02-01 | — | — | EP | disclosed |
| EP-2226192-B1 | DRYING SUBSTANCES, PREPARATION AND USE THEREOF | ORIDION MEDICAL 1987 LTD (IL) | 2016-08-31 | — | — | EP | disclosed |
| EP-2226116-B1 | Drying tube, preparation and use thereof | ORIDION MEDICAL 1987 LTD (IL) | 2016-04-20 | — | — | EP | disclosed |
| US-20150283519-A1 | DRYING SUBSTANCES, PREPARATION AND USE THEREOF | ORIDION MEDICAL 1987 LTD. (IL) | 2015-10-08 | — | — | US | disclosed |
| US-9090766-B2 | Drying substances, preparation and use thereof | ORIDION MEDICAL 1987 LTD. (IL) | 2015-07-28 | — | — | US | disclosed |
| US-9067035-B2 | Drying substances, preparation and use thereof | ORIDION MEDICAL (1987) LTD. (IL) | 2015-06-30 | — | — | US | disclosed |
| EP-2099770-B1 | PYRIDAZINONES AND FURAN-CONTAINING COMPOUNDS | SLOAN KETTERING INST CANCER (US) | 2015-06-10 | — | — | EP | disclosed |
| EP-1537095-B1 | PROCESS FOR PREPARING FUNCTIONALIZED GAMMA-BUTYROLACTONES FROM MUCOHALIC ACID | WARNER LAMBERT CO (US) | 2006-02-22 | — | — | EP | disclosed |
| US-20060000778-A1 | high-performance membrane designed for the selective removal of a polar fluid (water) from less polar fluids (organic solvents), by a pervaporation using a composite membrane contaiing ultrafiltration membrane as support ( e.g. cellulose acetate) and a crosslinked copolymer of anionic, cationic monomers | MCMASTER UNIVERSITY (CA) | 2006-01-05 | — | — | US | disclosed |
| US-6924377-B2 | Process for preparing highly functionalized γ-butyrolactams and γ-amino acids | WARNER-LAMBERT COMPANY (US) | 2005-08-02 | — | — | US | disclosed |
| EP-1537095-A1 | PROCESS FOR PREPARING FUNCTIONALIZED -BUTYROLACTIONES FROM MUCOHALIC ACID | Warner-Lambert Company LLC (US) | 2005-06-08 | — | — | EP | disclosed |
| EP-1499583-A1 | PROCESS FOR PREPARING HIGHLY FUNCTIONALIZED Y-BUTYROLACTAMS AND Y-AMINO ACIDS | Warner-Lambert Company LLC (US) | 2005-01-26 | — | — | EP | disclosed |
| WO-2004020424-A1 | PROCESS FOR PREPARING FUNCTIONALIZED -BUTYROLACTIONES FROM MUCOHALIC ACID | WARNER-LAMBERT COMPANY LLC (US) | 2004-03-11 | — | — | WO | disclosed |
| US-20030236415-A1 | Process for preparing highly functionalized gamma-butyrolactams and gamma-amino acids | BLAZECKA PETER G (CA) | 2003-12-25 | — | — | US | disclosed |
| US-20030225149-A1 | Process for preparing highly functionalized gamma-butyrolactams and gamma-amino acids | BLAZECKA PETER G (CA) | 2003-12-04 | — | — | US | disclosed |
| WO-2003093220-A1 | PROCESS FOR PREPARING HIGHLY FUNCTIONALIZED Y-BUTYROLACTAMS AND Y-AMINO ACIDS | WARNER-LAMBERT COMPANY LLC (US) | 2003-11-13 | — | — | WO | disclosed |
| US-4010182-A | Method for producing N-(4-fluorophenyl)-2,3,-dichloromaleimide | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JA) | 1977-03-01 | — | — | US | disclosed |