Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 11/20 | 0.65 |
| ▸ | RARA | P10276 | 2/20 | 0.56 |
| ▸ | RARG | P13631 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | THRA | P10827 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 3/20 | 0.45 |
| ▸ | MPL | P40238 | 2/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13175602 | 0.90 | RARB (0.64) | RARBRARARARGMEN1ALDH1A1 | |
| SCHEMBL9230278 | 0.85 | RARB (0.71) | RARBRARARARGMEN1ALDH1A1 | |
| SCHEMBL14175167 | 0.83 | RARB (0.66) | RARBRARARARGMEN1ALDH1A1 | |
| SCHEMBL2913907 | 0.82 | RARB (0.55) | RARBRARARARGMEN1ALDH1A1 | |
| SCHEMBL12437027 | 0.82 | RARB (0.55) | RARBRARARARGMEN1ALDH1A1 | |
| SCHEMBL2918064 | 0.82 | RARB (0.67) | RARBRARARARGMEN1ALDH1A1 | |
| SCHEMBL13310852 | 0.82 | RARB (0.68) | RARBRARARARGMEN1ALDH1A1 | |
| SCHEMBL14175164 | 0.82 | RARB (0.64) | RARBRARARARGMEN1ALDH1A1 | |
| SCHEMBL14175166 | 0.82 | RARB (0.64) | RARBRARARARGMEN1ALDH1A1 | |
| SCHEMBL9563730 | 0.82 | RARB (0.68) | RARBRARARARGMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1388538-B1 | Polymerisation Initiator | MERCK PATENT GMBH (DE) | 2010-09-01 | — | — | EP | disclosed |
| EP-1388538-A1 | Polymerisation Initiator | MERCK PATENT GmbH (DE) | 2004-02-11 | — | — | EP | disclosed |