Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11337639 | 0.78 | KMT2A (0.44) | TLR8ALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL5654447 | 0.76 | SMN1; SMN2 (0.46) | TLR8ALDH1A1TDP1KMT2ATSHR | |
| SCHEMBL2046856 | 0.71 | TSHR (0.39) | TLR8ALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL2045051 | 0.70 | — | — | |
| SCHEMBL9089789 | 0.70 | — | — | |
| SCHEMBL1195197 | 0.69 | MAPK1 (0.40) | TLR8ALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL1878978 | 0.69 | MEN1 (0.38) | TLR8ALDH1A1TDP1KMT2AMEN1 | |
| SCHEMBL12798235 | 0.67 | — | — | |
| SCHEMBL12111894 | 0.67 | — | — | |
| SCHEMBL9279364 | 0.67 | CSNK2A2 (0.39) | ALDH1A1KMT2ALMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116763781-A | Triazole derivative and preparation method and application thereof | 华东师范大学 | 2023-09-19 | — | — | CN | disclosed |