Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13370393 | 0.90 | ESR1 (0.57) | ESR1CYP19A1ESR2MAPK1MAPT | |
| SCHEMBL11025481 | 0.90 | ESR1 (0.57) | ESR1CYP19A1ESR2MAPK1MAPT | |
| SCHEMBL11025397 | 0.79 | MAPK1 (0.53) | ESR1CYP19A1ESR2MAPK1MAPT | |
| SCHEMBL11024033 | 0.77 | CYP3A4 (0.49) | ESR1CYP19A1ESR2MAPK1MAPT | |
| 4-Nitrobenzoic Acid Ethyl Ester SCHEMBL21644730 | 0.76 | KCNJ1 (0.64) | ESR1ESR2MAPK1MAPTALDH1A1 | |
| SCHEMBL3629746 | 0.75 | ESR1 (0.56) | ESR1CYP19A1ESR2MAPK1ALDH1A1 | |
| 4-Nitrobenzoic Acid SCHEMBL21644729 | 0.75 | TDP1 (0.66) | MAPK1MAPTALDH1A1KDM4EGAA | |
| SCHEMBL11110091 | 0.75 | MAPK1 (0.54) | ESR1CYP19A1ESR2MAPK1MAPT | |
| SCHEMBL11110090 | 0.75 | MAPK1 (0.54) | ESR1CYP19A1ESR2MAPK1MAPT | |
| 4-Nitrobenzoic Acid Ethyl Ester SCHEMBL1500579 | 0.74 | KCNJ1 (0.68) | ESR1ESR2MAPK1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117050113-B | Preparation method of tetravalent platinum nano-drug particles | 南方医科大学南方医院 | 2024-03-19 | — | — | CN | disclosed |
| CN-117050113-A | Preparation method of tetravalent platinum nano-drug particles | 南方医科大学南方医院 | 2023-11-14 | — | — | CN | disclosed |