Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 15/20 | 0.55 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29147877 | 0.92 | KDM1A (0.52) | KDM1ACYP11B2CYP11B1MTOR | |
| SCHEMBL29105947 | 0.85 | KDM1A (0.48) | KDM1ACYP11B2 | |
| SCHEMBL26695563 | 0.84 | KDM1A (0.49) | KDM1ACYP11B2CYP11B1GPR119 | |
| SCHEMBL29147910 | 0.83 | KDM1A (0.48) | KDM1ACYP11B2CYP11B1GPR119 | |
| SCHEMBL29106006 | 0.83 | SMN1; SMN2 (0.54) | KDM1A | |
| SCHEMBL29105970 | 0.83 | KDM1A (0.48) | KDM1A | |
| SCHEMBL26695734 | 0.81 | KDM1A (0.49) | KDM1ACYP11B2CYP11B1GPR119 | |
| SCHEMBL29106005 | 0.81 | KDM4E (0.48) | KDM1A | |
| SCHEMBL29147912 | 0.81 | KDM1A (0.46) | KDM1ACYP11B2 | |
| SCHEMBL29106003 | 0.80 | KDM1A (0.42) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117062813-A | Polycyclic compound and application thereof | 四川汇宇制药股份有限公司 | 2023-11-14 | — | — | CN | disclosed |