Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.83 |
| ▸ | LCK | P06239 | 1/20 | 0.70 |
| ▸ | YES1 | P07947 | 1/20 | 0.70 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28574044 | 0.93 | BTK (0.73) | BTKLCKYES1PTK6 | |
| SCHEMBL28574056 | 0.91 | BTK (0.72) | BTK | |
| SCHEMBL28579291 | 0.91 | BTK (0.74) | BTK | |
| SCHEMBL19898376 | 0.91 | BTK (1.00) | BTKLCKYES1PTK6 | |
| SCHEMBL19898141 | 0.91 | BTK (0.86) | BTK | |
| SCHEMBL29106913 | 0.91 | BTK (0.86) | BTK | |
| SCHEMBL28574637 | 0.90 | BTK (0.75) | BTK | |
| SCHEMBL29841457 | 0.90 | BTK (0.75) | BTK | |
| SCHEMBL19898447 | 0.90 | BTK (1.00) | BTKLCKYES1PTK6 | |
| SCHEMBL19898001 | 0.89 | BTK (0.92) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117042769-A | Substituted pyrrolopyrimidines and pyrazolopyrimidines as Bruton's Tyrosine Kinase (BTK) degrading agents | 冰洲石生物科技公司 | 2023-11-10 | — | — | CN | disclosed |