Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 12/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29109304 | 1.00 | GNRHR (0.38) | GNRHRMIFTAAR1MGLLCA2 | |
| SCHEMBL29109348 | 0.87 | PIK3CD (0.40) | — | |
| SCHEMBL29109352 | 0.87 | PIK3CD (0.40) | — | |
| SCHEMBL29109340 | 0.80 | PIK3CD (0.35) | GNRHRAKR1C3AKR1C2 | |
| SCHEMBL30604517 | 0.80 | PIK3CD (0.35) | GNRHRAKR1C3AKR1C2 | |
| SCHEMBL29109338 | 0.80 | PIK3CD (0.35) | GNRHRAKR1C3AKR1C2 | |
| SCHEMBL29109309 | 0.80 | PIK3CD (0.36) | — | |
| SCHEMBL29109305 | 0.80 | PIK3CD (0.36) | — | |
| SCHEMBL29109341 | 0.79 | PIK3CD (0.33) | — | |
| SCHEMBL29109343 | 0.79 | PIK3CD (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117088867-A | Inhalable aromatic ring thiazide and analogue, pharmaceutical composition containing inhalable aromatic ring thiazide and analogue and application of inhalable aromatic ring thiazide and analogue in anti-inflammatory and anti-tumor | 杭州百诚医药科技股份有限公司 | 2023-11-21 | — | — | CN | disclosed |