SCHEMBL29109342

SCHEMBL29109342

CC(N)C1=Cc2cccc(Cl)c2S(=O)(=O)N1c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PIK3R1 P27986 9/20 0.39
PIK3CD O00329 8/20 0.39
PIK3CB P42338 4/20 0.39
PIK3CG P48736 4/20 0.39
PIK3CA P42336 2/20 0.39
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
NFKB1 P19838 1/20 0.36
PNMT P11086 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
GLA P06280 1/20 0.36
RXFP1 Q9HBX9 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29109339 1.00 PIK3R1 (0.39) PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA
SCHEMBL29109275 0.90 PIK3R1 (0.33) PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA
SCHEMBL29109273 0.90 PIK3R1 (0.33) PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA
SCHEMBL31575987 0.90 PIK3R1 (0.35) PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA
SCHEMBL31603428 0.90 PIK3R1 (0.35) PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA
SCHEMBL31603657 0.87 PIK3CD (0.34) PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA
SCHEMBL31575909 0.87 PIK3CD (0.34) PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA
SCHEMBL31575926 0.86 PIK3R1 (0.40) PIK3R1PIK3CDPIK3CBPIK3CGPIK3CA
SCHEMBL29109352 0.84 PIK3CD (0.40) PIK3R1PIK3CD
SCHEMBL29109348 0.84 PIK3CD (0.40) PIK3R1PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120020131-A Aromatic ring benzothiazine derivative and medical application thereof 杭州百诚医药科技股份有限公司 2025-05-20 CN disclosed
CN-117088867-A Inhalable aromatic ring thiazide and analogue, pharmaceutical composition containing inhalable aromatic ring thiazide and analogue and application of inhalable aromatic ring thiazide and analogue in anti-inflammatory and anti-tumor 杭州百诚医药科技股份有限公司 2023-11-21 CN disclosed