Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | FYN | P06241 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26628786 | 0.89 | KMT2A (0.55) | HTTKCNJ1KDM4EMAPTKMT2A | |
| SCHEMBL221039 | 0.77 | KCNJ1 (0.54) | HTTKCNJ1KDM4EMAPTKMT2A | |
| SCHEMBL29109429 | 0.77 | MEN1 (0.47) | KCNJ1KDM4EMAPTKMT2ASMN1; SMN2 | |
| SCHEMBL31463887 | 0.77 | HCRTR1 (0.57) | KCNJ1KDM4EMAPTKMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4902833 | 0.76 | KCNJ1 (0.53) | HTTKCNJ1KDM4EMAPTKMT2A | |
| SCHEMBL18227502 | 0.76 | KDM4E (0.61) | HTTKCNJ1KDM4EMAPTKMT2A | |
| SCHEMBL2217484 | 0.74 | KDM4E (0.55) | HTTKDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL167736 | 0.74 | CYP2A13 (0.47) | HTTKDM4EMAPTKMT2AALDH1A1 | |
| SCHEMBL166409 | 0.74 | CYP2A13 (0.47) | HTTKDM4EMAPTKMT2AALDH1A1 | |
| SCHEMBL16400206 | 0.73 | KDM4E (0.74) | HTTKDM4EMAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116648250-A | Novel quinazoline derivatives as SOS1 inhibitors and uses thereof | 韩美药品株式会社 | 2023-08-25 | — | — | CN | disclosed |