Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.85 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.85 |
| ▸ | CSF1R | P07333 | 13/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2911828 | 0.93 | CSF1R (0.78) | KCNH2SCN5ACSF1RCYP3A4CYP2C9 | |
| SCHEMBL2913343 | 0.92 | KCNH2 (0.72) | KCNH2SCN5ACSF1RCYP3A4CYP2C9 | |
| SCHEMBL1276312 | 0.92 | KCNH2 (1.00) | KCNH2SCN5ACSF1R | |
| SCHEMBL2911186 | 0.91 | KCNH2 (0.71) | KCNH2SCN5ACSF1R | |
| SCHEMBL2905897 | 0.91 | KCNH2 (0.84) | KCNH2SCN5ACSF1R | |
| SCHEMBL2912202 | 0.91 | KCNH2 (0.86) | KCNH2SCN5ACSF1R | |
| SCHEMBL2914241 | 0.90 | KCNH2 (0.85) | KCNH2SCN5ACSF1R | |
| SCHEMBL2904231 | 0.90 | KCNH2 (0.82) | KCNH2SCN5ACSF1R | |
| Hydrochloric Acid SCHEMBL2904605 | 0.90 | KCNH2 (0.82) | KCNH2SCN5ACSF1R | |
| SCHEMBL2912427 | 0.90 | KCNH2 (0.85) | KCNH2SCN5ACSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010496-B1 | 4-ANILINOQUINOLINE-3-CARBOXAMIDES AS CSF-1R KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2010-08-25 | — | — | EP | disclosed |