Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.56 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.56 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.38 |
| ▸ | FEN1 | P39748 | 2/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 5/20 | 0.34 |
| ▸ | EGFR | P00533 | 3/20 | 0.32 |
| ▸ | FYN | P06241 | 2/20 | 0.32 |
| ▸ | VCP | P55072 | 2/20 | 0.32 |
| ▸ | YES1 | P07947 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.32 |
| ▸ | BTK | Q06187 | 2/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30717990 | 0.85 | CYP3A4 (0.54) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL26627319 | 0.85 | CYP3A4 (0.54) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL29452581 | 0.81 | CYP3A4 (0.51) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL22677151 | 0.81 | CYP3A4 (0.51) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL26627316 | 0.77 | CYP3A4 (0.44) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL22658735 | 0.76 | CYP3A4 (0.64) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL31398933 | 0.76 | FGFR1 (0.51) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL26106772 | 0.75 | CYP3A4 (0.56) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL29407664 | 0.75 | CYP3A4 (0.56) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL24459761 | 0.75 | FGFR1 (0.73) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116903628-A | FGFR2 inhibitors and methods of use | 深圳福沃药业有限公司 | 2023-10-20 | — | — | CN | disclosed |