Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | ESR1 | P03372 | 2/20 | 0.60 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29110419 | 0.88 | POLB (0.77) | POLBESR1ESR2KCNH2HRH3 | |
| SCHEMBL28924717 | 0.87 | POLB (0.59) | POLBESR1ESR2KCNH2HRH3 | |
| SCHEMBL29110406 | 0.86 | ESR1 (0.58) | POLBESR1ESR2ALDH1A1HSD17B10 | |
| SCHEMBL29110476 | 0.86 | POLB (0.61) | POLBESR1ESR2KCNH2HRH3 | |
| SCHEMBL29110467 | 0.86 | KMT2A (0.60) | POLBESR1ESR2KCNH2HRH3 | |
| SCHEMBL2118476 | 0.82 | MAPK1 (0.76) | POLBESR1ESR2HRH3ALDH1A1 | |
| SCHEMBL31463104 | 0.77 | NPC1 (0.71) | POLBESR1ESR2KCNH2HRH3 | |
| SCHEMBL30089874 | 0.77 | MAPT (0.69) | POLBESR1ESR2HSD17B10MAPK1 | |
| SCHEMBL30089869 | 0.77 | POLB (0.73) | POLBESR1ESR2KCNH2HRH3 | |
| SCHEMBL29110444 | 0.77 | MAPT (0.69) | POLBESR1ESR2HSD17B10MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521262-B | Preparation method of quinazolinone containing phenyl and composition thereof, and application of quinazolinone and composition in resisting kiwi fruit canker | 贵州理工学院 | 2024-04-05 | — | — | CN | claimed |
| CN-115677803-B | Preparation method of glycoside derivative containing quinazoline structure and composition thereof and application of glycoside derivative and composition for preventing and treating kiwi fruit canker | 贵州理工学院 | 2025-03-28 | — | — | CN | disclosed |
| CN-115521262-B | Preparation method of quinazolinone containing phenyl and composition thereof, and application of quinazolinone and composition in resisting kiwi fruit canker | 贵州理工学院 | 2024-04-05 | — | — | CN | disclosed |
| CN-115677803-A | Preparation method of glucoside derivative containing quinazoline structure, preparation method of composition of glucoside derivative and application of composition in prevention and treatment of kiwifruit canker | 贵州理工学院 | 2023-02-03 | — | — | CN | disclosed |
| CN-115521262-A | Preparation method of phenyl-containing quinazolinone and composition thereof and application of phenyl-containing quinazolinone in resisting kiwifruit canker | 贵州理工学院 | 2022-12-27 | — | — | CN | disclosed |