Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.71 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30089868 | 1.00 | HSD17B10 (0.71) | HSD17B10GAAMEN1KMT2APOLB | |
| SCHEMBL29110471 | 0.87 | HSD17B10 (0.68) | HSD17B10GAAMEN1KMT2APOLB | |
| SCHEMBL30726108 | 0.84 | HDAC1 (0.57) | HSD17B10POLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL16596948 | 0.84 | HDAC1 (0.57) | HSD17B10POLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL16596950 | 0.84 | PIK3CD (0.52) | HSD17B10POLBSMN1; SMN2HRH3KCNH2 | |
| SCHEMBL357631 | 0.83 | HSD17B10 (0.50) | HSD17B10GAAMEN1KMT2AALDH1A1 | |
| SCHEMBL29110437 | 0.80 | HSD17B10 (0.69) | HSD17B10GAAMEN1KMT2APOLB | |
| SCHEMBL30089887 | 0.80 | HSD17B10 (0.69) | HSD17B10GAAMEN1KMT2APOLB | |
| SCHEMBL29110466 | 0.79 | HSD17B10 (0.72) | HSD17B10GAAMEN1KMT2APOLB | |
| SCHEMBL30089880 | 0.79 | HSD17B10 (0.72) | HSD17B10GAAMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521262-B | Preparation method of quinazolinone containing phenyl and composition thereof, and application of quinazolinone and composition in resisting kiwi fruit canker | 贵州理工学院 | 2024-04-05 | — | — | CN | disclosed |
| CN-115677803-A | Preparation method of glucoside derivative containing quinazoline structure, preparation method of composition of glucoside derivative and application of composition in prevention and treatment of kiwifruit canker | 贵州理工学院 | 2023-02-03 | — | — | CN | disclosed |
| CN-115521262-A | Preparation method of phenyl-containing quinazolinone and composition thereof and application of phenyl-containing quinazolinone in resisting kiwifruit canker | 贵州理工学院 | 2022-12-27 | — | — | CN | disclosed |