Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | TRPV4 | Q9HBA0 | 8/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.45 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30089872 | 1.00 | HRH3 (0.58) | HRH3KCNH2GRM1HDAC1HDAC10 | |
| SCHEMBL28924664 | 0.88 | HRH3 (0.57) | HRH3KCNH2HDAC1HDAC10HDAC8 | |
| SCHEMBL30149484 | 0.88 | HRH3 (0.57) | HRH3KCNH2HDAC1HDAC10HDAC8 | |
| SCHEMBL30089881 | 0.86 | HSD17B10 (0.66) | HRH3KCNH2HDAC1HDAC10HDAC8 | |
| SCHEMBL29110474 | 0.86 | HSD17B10 (0.66) | HRH3KCNH2HDAC1HDAC10HDAC8 | |
| SCHEMBL29110429 | 0.86 | HRH3 (0.57) | HRH3KCNH2GRM1HDAC1HDAC10 | |
| SCHEMBL29110398 | 0.83 | KCNH2 (0.57) | HRH3KCNH2GRM1HDAC1HDAC10 | |
| SCHEMBL30089875 | 0.83 | KCNH2 (0.57) | HRH3KCNH2GRM1HDAC1HDAC10 | |
| SCHEMBL29110405 | 0.81 | HRH3 (0.61) | HRH3KCNH2GRM1HDAC1HDAC10 | |
| SCHEMBL29110432 | 0.77 | ESR1 (0.50) | HRH3KCNH2GRM1HDAC1HDAC10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521262-B | Preparation method of quinazolinone containing phenyl and composition thereof, and application of quinazolinone and composition in resisting kiwi fruit canker | 贵州理工学院 | 2024-04-05 | — | — | CN | disclosed |
| CN-115677803-A | Preparation method of glucoside derivative containing quinazoline structure, preparation method of composition of glucoside derivative and application of composition in prevention and treatment of kiwifruit canker | 贵州理工学院 | 2023-02-03 | — | — | CN | disclosed |
| CN-115521262-A | Preparation method of phenyl-containing quinazolinone and composition thereof and application of phenyl-containing quinazolinone in resisting kiwifruit canker | 贵州理工学院 | 2022-12-27 | — | — | CN | disclosed |