Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 19/20 | 0.71 |
| ▸ | HDAC1 | Q13547 | 14/20 | 0.71 |
| ▸ | HDAC8 | Q9BY41 | 12/20 | 0.71 |
| ▸ | HDAC3 | O15379 | 11/20 | 0.71 |
| ▸ | HDAC2 | Q92769 | 11/20 | 0.71 |
| ▸ | HDAC10 | Q969S8 | 11/20 | 0.71 |
| ▸ | NCOR2 | Q9Y618 | 11/20 | 0.71 |
| ▸ | HDAC4 | P56524 | 11/20 | 0.71 |
| ▸ | HDAC7 | Q8WUI4 | 10/20 | 0.71 |
| ▸ | HDAC11 | Q96DB2 | 10/20 | 0.71 |
| ▸ | HDAC9 | Q9UKV0 | 10/20 | 0.71 |
| ▸ | HDAC5 | Q9UQL6 | 10/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29110792 | 0.87 | HDAC6 (0.67) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL29605505 | 0.87 | HDAC6 (0.67) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL29110809 | 0.85 | HDAC6 (0.66) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL29606039 | 0.85 | HDAC6 (0.66) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL29110804 | 0.82 | HDAC6 (0.67) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL29606448 | 0.82 | HDAC6 (0.67) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL29110774 | 0.81 | HDAC6 (0.63) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL29605449 | 0.81 | HDAC6 (0.63) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL29110797 | 0.81 | HDAC6 (0.73) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL29110762 | 0.79 | HDAC6 (0.58) | HDAC6HDAC1HDAC8HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621194-B | 4-methylene-N-hydroxybenzoamide compound and application thereof | 沈阳药科大学 | 2023-08-29 | — | — | CN | disclosed |
| CN-114621194-A | 4-methylene-N-hydroxybenzamide compound and application thereof | 沈阳药科大学 | 2022-06-14 | — | — | CN | disclosed |