Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 13/20 | 0.54 |
| ▸ | HTR1A | P08908 | 9/20 | 0.47 |
| ▸ | HTR6 | P50406 | 7/20 | 0.43 |
| ▸ | HTR2C | P28335 | 6/20 | 0.43 |
| ▸ | HTR2B | P41595 | 6/20 | 0.43 |
| ▸ | HTR1D | P28221 | 5/20 | 0.43 |
| ▸ | HTR1E | P28566 | 5/20 | 0.43 |
| ▸ | DRD3 | P35462 | 5/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.43 |
| ▸ | HRH1 | P35367 | 4/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27084849 | 0.98 | HTR2A (0.56) | HTR2AHTR1AHTR6HTR2CHTR2B | |
| SCHEMBL27084855 | 0.94 | HTR2A (0.51) | HTR2AHTR1AHTR6HTR2CHTR2B | |
| SCHEMBL27084755 | 0.94 | HTR2A (0.53) | HTR2AHTR1AHTR6HTR2CHTR2B | |
| SCHEMBL27084793 | 0.92 | HTR2A (0.55) | HTR2AHTR1AHTR6HTR2CHTR2B | |
| SCHEMBL27084749 | 0.91 | HTR2A (0.58) | HTR2AHTR1AHTR6HTR2CHTR2B | |
| SCHEMBL27084958 | 0.91 | HTR2A (0.49) | HTR2AHTR1AHTR6HTR2CHTR2B | |
| SCHEMBL27084980 | 0.91 | HTR2A (0.55) | HTR2AHTR1AHTR6HTR2CHTR2B | |
| SCHEMBL27084834 | 0.89 | HTR2A (0.54) | HTR2AHTR1AHTR6HTR2CHTR2B | |
| SCHEMBL29112599 | 0.89 | HTR2A (0.60) | HTR2AHTR1AHTR6HTR2CHTR2B | |
| SCHEMBL27084672 | 0.89 | HTR2A (0.56) | HTR2AHTR1AHTR6HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120415-A | Modified indole alkaloids for therapeutic use | 指南针探路者有限公司 | 2023-11-24 | — | — | CN | disclosed |