Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.42 |
| ▸ | PI4KA | P42356 | 2/20 | 0.42 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.42 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.40 |
| ▸ | ADCY5 | O95622 | 2/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | AHCY | P23526 | 1/20 | 0.38 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.38 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | POLA1 | P09884 | 1/20 | 0.38 |
| ▸ | POLG | P54098 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2906000 | 0.82 | CYP3A4 (0.50) | CYP3A4SLC22A6FGFR1ADORA2AADORA1 | |
| SCHEMBL2904804 | 0.81 | KDM4E (0.38) | — | |
| SCHEMBL4279921 | 0.77 | CYP3A4 (0.47) | CYP3A4SLC22A6FGFR1ADORA2AADORA1 | |
| SCHEMBL4267091 | 0.76 | ADORA2A (0.50) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL2913580 | 0.72 | CYP3A4 (0.50) | CYP3A4SLC22A6FGFR1ADORA2AADORA1 | |
| SCHEMBL3290251 | 0.72 | FGFR1 (0.60) | CYP3A4SLC22A6FGFR1ADORA2AADORA1 | |
| SCHEMBL28797058 | 0.70 | SLC22A6 (0.67) | CYP3A4SLC22A6FGFR1ADORA2AADORA1 | |
| SCHEMBL3293432 | 0.70 | FGFR1 (0.47) | CYP3A4SLC22A6FGFR1ADORA2AADORA1 | |
| SCHEMBL4558842 | 0.69 | CYP3A4 (0.70) | CYP3A4ADORA2AADORA1AHCYFAP | |
| SCHEMBL8395927 | 0.69 | CYP3A4 (0.70) | CYP3A4ADORA2AADORA1AHCYFAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358198-B1 | NOVEL ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES, SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | LG LIFE SCIENCES LTD (KR) | 2010-08-25 | — | — | EP | claimed |