Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.48 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | NOS3 | P29474 | 4/20 | 0.32 |
| ▸ | NOS1 | P29475 | 4/20 | 0.32 |
| ▸ | NOS2 | P35228 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28991608 | 1.00 | TRIM24 (0.48) | TRIM24TRIM33ALDH1A1NOS3NOS1 | |
| SCHEMBL28991505 | 1.00 | TRIM24 (0.48) | TRIM24TRIM33ALDH1A1NOS3NOS1 | |
| SCHEMBL28781377 | 0.90 | — | — | |
| SCHEMBL26644594 | 0.82 | TRIM24 (0.58) | TRIM24TRIM33ALDH1A1NOS3NOS1 | |
| SCHEMBL30656141 | 0.82 | TRIM24 (0.58) | TRIM24TRIM33ALDH1A1NOS3NOS1 | |
| SCHEMBL13800327 | 0.78 | — | — | |
| SCHEMBL970948 | 0.74 | — | — | |
| SCHEMBL25380098 | 0.67 | TRIM24 (1.00) | TRIM24TRIM33ALDH1A1 | |
| Cyclohexanone SCHEMBL3299 | 0.67 | — | — | |
| Cyclohexanone SCHEMBL713141 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867726-B | Small molecule inhibitors of KRAS G12C mutants | 默沙东有限责任公司 | 2023-11-28 | — | — | CN | disclosed |