Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | ALPL | P05186 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 3/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid Methyl Ester SCHEMBL27841730 | 0.93 | CA12 (0.41) | CA12CA1CA2CA9NFE2L2 | |
| SCHEMBL29682155 | 0.92 | — | — | |
| SCHEMBL10549246 | 0.92 | — | — | |
| SCHEMBL29113235 | 0.87 | CA12 (0.42) | CA12CA1CA2CA9TGM2 | |
| Acetic Acid SCHEMBL27841728 | 0.85 | KDM4C (0.41) | CA12CA1CA2CA9TGM2 | |
| SCHEMBL11541406 | 0.78 | PTGS1 (0.51) | CA12CA1CA2CA9PTGS1 | |
| SCHEMBL9372692 | 0.77 | — | — | |
| SCHEMBL5700142 | 0.75 | — | — | |
| Formic Acid SCHEMBL28858365 | 0.74 | CA12 (0.49) | CA12CA1CA2CA9MAOA | |
| SCHEMBL29935810 | 0.74 | ERN1 (0.49) | CA12CA1CA2CA9MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116874466-B | N-substituted dioxocyclobutylamino-3-hydroxy-pyridinecarboxamides as CCR6 inhibitors | PFIZER INC. (US) | 2026-05-26 | — | — | CN | disclosed |
| CN-116874466-A | N-substituted dioxocyclobutylamino-3-hydroxy-pyridinecarboxamides as CCR6 inhibitors | 辉瑞公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-112672791-B | N-substituted dioxocyclobutylamino-3-hydroxy-pyridinecarboxamides as CCR6 inhibitors | 辉瑞公司 | 2023-10-03 | — | — | CN | disclosed |