Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.66 |
| ▸ | INSR | P06213 | 2/20 | 0.57 |
| ▸ | IGF1R | P08069 | 2/20 | 0.57 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26906680 | 0.94 | EGFR (0.61) | EGFRINSRIGF1RALK | |
| SCHEMBL26906725 | 0.93 | EGFR (0.56) | EGFRINSRIGF1RALK | |
| SCHEMBL26906674 | 0.91 | EGFR (0.64) | EGFRINSRIGF1RALK | |
| SCHEMBL26906853 | 0.91 | EGFR (0.71) | EGFRINSRIGF1RALK | |
| SCHEMBL26906530 | 0.91 | EGFR (0.67) | EGFRINSRIGF1RALK | |
| SCHEMBL26906842 | 0.90 | EGFR (0.62) | EGFRALK | |
| SCHEMBL26906534 | 0.90 | EGFR (0.61) | EGFRINSRIGF1RALK | |
| SCHEMBL26906605 | 0.90 | EGFR (0.56) | EGFRINSRIGF1RALK | |
| SCHEMBL26906514 | 0.90 | EGFR (0.66) | EGFRINSRIGF1RALK | |
| SCHEMBL26906645 | 0.90 | EGFR (0.66) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120424-A | Pyrimidine derivatives having protein kinase inhibitory activity and therapeutic combinations comprising the same | 泰拉佩克斯有限公司 | 2023-11-24 | — | — | CN | disclosed |