Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.49 |
| ▸ | GRB2 | P62993 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30643726 | 1.00 | PTPN1 (0.49) | PTPN1GRB2MDM2PSMB5REN | |
| SCHEMBL29115273 | 1.00 | PTPN1 (0.49) | PTPN1GRB2MDM2PSMB5REN | |
| SCHEMBL30643729 | 0.91 | MDM2 (0.49) | PTPN1MDM2BACE1 | |
| SCHEMBL29115025 | 0.91 | MDM2 (0.49) | PTPN1MDM2BACE1 | |
| SCHEMBL29115023 | 0.91 | MDM2 (0.49) | PTPN1MDM2BACE1 | |
| SCHEMBL29877744 | 0.88 | PTPN1 (0.49) | PTPN1GRB2MDM2PSMB5MMP3 | |
| SCHEMBL29115128 | 0.88 | PTPN1 (0.49) | PTPN1GRB2MDM2PSMB5MMP3 | |
| SCHEMBL29115131 | 0.88 | PTPN1 (0.49) | PTPN1GRB2MDM2PSMB5MMP3 | |
| SCHEMBL29308019 | 0.86 | PSMB5 (0.54) | PSMB5MMP3 | |
| SCHEMBL30943616 | 0.86 | PTPN1 (0.57) | PTPN1GRB2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117120097-A | Selective drug release of internalized bioactive compound conjugates | 思进公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-117120098-A | Selective drug release of internalized bioactive compound conjugates | 思进公司 | 2023-11-24 | — | — | CN | disclosed |