Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CDC42 | P60953 | 1/20 | 0.40 |
| ▸ | RAC1 | P63000 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28979 | 0.78 | HTR2A (0.49) | HTR2CROCK1SLC6A2CYP1A2CYP2A6 | |
| SCHEMBL2502244 | 0.77 | KDM4E (0.36) | HTR2CCYP1A2MAPT | |
| SCHEMBL30967900 | 0.77 | HTR2A (0.50) | HTR2CROCK1HTR6SLC6A2CYP2A6 | |
| SCHEMBL2073701 | 0.77 | PRKCI (0.53) | HTR2CPOLBMAPTLMNA | |
| SCHEMBL850727 | 0.77 | HTR2C (0.50) | HTR2CSLC6A2SLC6A4PRMT5MAPT | |
| SCHEMBL3327014 | 0.77 | MAPT (0.33) | HTR2CMAPT | |
| SCHEMBL30949143 | 0.77 | HTR2A (0.50) | HTR2CSLC6A2SLC6A4PRMT5MAPT | |
| SCHEMBL29533363 | 0.75 | HTR2C (0.35) | HTR2CROCK1CYP1A2MAPTCYP2C9 | |
| SCHEMBL1856356 | 0.75 | KDM4E (0.46) | POLBTUBB1MAPTLMNACYP2C9 | |
| SCHEMBL597518 | 0.75 | HTR2C (0.58) | HTR2CROCK1POLBHTR6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025760-A1 | PROCESS FOR THE BORYLATION OF ARENES AND HETEROARYLS | THE UNIVERSITY OF MANCHESTER (GB) | 2012-03-01 | — | — | WO | disclosed |