Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2912394 | 0.78 | KDM4E (0.32) | CTSAACHEKDM4EALDH1A1POLB | |
| SCHEMBL12999105 | 0.77 | KDM4E (0.32) | CTSAACHEKDM4EALDH1A1POLB | |
| SCHEMBL12999093 | 0.76 | KDM4E (0.31) | CTSAACHEKDM4EALDH1A1POLB | |
| SCHEMBL13328651 | 0.73 | — | — | |
| SCHEMBL3288249 | 0.71 | — | — | |
| SCHEMBL3146365 | 0.70 | — | — | |
| SCHEMBL13714863 | 0.69 | — | — | |
| SCHEMBL3288254 | 0.69 | — | — | |
| SCHEMBL13328629 | 0.68 | — | — | |
| SCHEMBL14942960 | 0.67 | CTSA (0.36) | CTSAACHEKDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358198-B1 | NOVEL ACYCLIC NUCLEOSIDE PHOSPHONATE DERIVATIVES, SALTS THEREOF AND PROCESS FOR THE PREPARATION OF THE SAME | LG LIFE SCIENCES LTD (KR) | 2010-08-25 | — | — | EP | disclosed |