Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | YAP1 | P46937 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 2/20 | 0.41 |
| ▸ | JAK3 | P52333 | 2/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31281239 | 1.00 | ESR2 (0.50) | ESR2NR1H2NPC1RAB9AYAP1 | |
| SCHEMBL22504373 | 1.00 | ESR2 (0.50) | ESR2NR1H2NPC1RAB9AYAP1 | |
| SCHEMBL20509999 | 0.85 | PPARG (0.44) | NPC1PPARGPPARDPPARAHCRTR1 | |
| SCHEMBL20509998 | 0.85 | PPARG (0.44) | NPC1PPARGPPARDPPARAHCRTR1 | |
| SCHEMBL1787313 | 0.81 | ESR2 (0.59) | ESR2NR1H2NPC1RAB9AJAK2 | |
| SCHEMBL1788257 | 0.80 | ESR2 (0.57) | ESR2NR1H2NPC1RAB9AJAK2 | |
| SCHEMBL18480928 | 0.78 | PPARG (0.43) | NPC1RAB9APPARGPPARDALDH1A1 | |
| SCHEMBL5663801 | 0.77 | ESR2 (0.57) | ESR2NR1H2NPC1RAB9AJAK2 | |
| SCHEMBL1790023 | 0.77 | ESR2 (0.54) | ESR2NR1H2NPC1RAB9AJAK2 | |
| SCHEMBL5662595 | 0.77 | ESR2 (0.44) | ESR2NR1H2NPC1RAB9AJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110891938-B | Tetrahydro-benzo [ D ] azepine derivatives as GPR120 modulators | 卡尔丹治疗有限公司 | 2023-10-31 | — | — | CN | disclosed |