SCHEMBL2912477

SCHEMBL2912477

C=C(C)C(=O)OCCCCCCCC.C=C(C)C(=O)OCCCCCCCC(C)C

nearest known ligand 0.77

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.77
THRB P10828 1/20 0.46
NAAA Q02083 1/20 0.44
POLB P06746 1/20 0.44
APEX1 P27695 1/20 0.44
HTT P42858 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
RAD52 P43351 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
EPHX1 P07099 1/20 0.42
FAAH O00519 2/20 0.42
ALDH1A1 P00352 1/20 0.40
ZDHHC7 Q9NXF8 1/20 0.40
CES2 O00748 1/20 0.40
HCAR2 Q8TDS4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31207506 1.00 TSHR (0.77) TSHRTHRBNAAAPOLBAPEX1
SCHEMBL7736289 1.00 TSHR (0.77) TSHRTHRBNAAAPOLBAPEX1
SCHEMBL9658227 1.00 TSHR (0.77) TSHRTHRBNAAAPOLBAPEX1
SCHEMBL29580544 0.97 TSHR (0.72) TSHRTHRBNAAAPOLBAPEX1
SCHEMBL7526979 0.94 TSHR (0.69) TSHRTHRBNAAAPOLBAPEX1
SCHEMBL5609613 0.94 TSHR (0.77) TSHRTHRBNAAAPOLBAPEX1
SCHEMBL30338 0.93 TSHR (0.65) TSHRTHRBNAAAPOLBAPEX1
SCHEMBL216465 0.93 TSHR (0.65) TSHRTHRBNAAAPOLBAPEX1
SCHEMBL19991477 0.93 TSHR (0.65) TSHRTHRBNAAAPOLBAPEX1
SCHEMBL9947749 0.93 TSHR (0.65) TSHRTHRBNAAAPOLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1383625-B1 A PROCESS OF MAKING A SHAPED PRODUCT NORSK HYDRO AS (NO) 2010-09-08 EP disclosed
US-7004374-B2 Process of making a shaped product NORSK HYDRO ASA (NO) 2006-02-28 US disclosed
US-20040164125-A1 Process of making a shaped product NORSK HYDRO ASA (NO) 2004-08-26 US disclosed
EP-1383625-A1 A PROCESS OF MAKING A SHAPED PRODUCT NORSK HYDRO ASA (NO) 2004-01-28 EP disclosed
WO-2003037559-A1 A PROCESS OF MAKING A SHAPED PRODUCT NORSK HYDRO ASA (NO) 2003-05-08 WO disclosed
WO-2003015979-A1 ALUMINIUM PRODUCT HAVING EXCELLENT BRAZING CHARACTERISTICS NORSK HYDRO ASA (NO) 2003-02-27 WO disclosed
EP-1232040-A1 ALUMINIUM PRODUCT WITH EXCELLENT BRAZING CHARACTERISTICS NORSK HYDRO ASA (NO) 2002-08-21 EP disclosed
WO-2001038040-A1 ALUMINIUM PRODUCT WITH EXCELLENT BRAZING CHARACTERISTICS NORSK HYDRO ASA (NO) 2001-05-31 WO disclosed