Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | BRS3 | P32247 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29125764 | 0.88 | TSHR (0.32) | TSHRLMNAGRM4HTR1AADRA2A | |
| SCHEMBL29125928 | 0.80 | TSHR (0.49) | TSHRLMNAKMT2AMMP13HSD17B10 | |
| SCHEMBL29128341 | 0.78 | GRM4 (0.31) | LMNAKMT2AGRM4 | |
| SCHEMBL29125760 | 0.73 | TSHR (0.45) | TSHRLMNAKMT2AMMP13HSD17B10 | |
| SCHEMBL29126036 | 0.72 | TSHR (0.46) | TSHRLMNAKMT2AMMP13HSD17B10 | |
| SCHEMBL29128506 | 0.71 | — | — | |
| SCHEMBL29125693 | 0.69 | TSHR (0.46) | TSHRLMNAKMT2AMMP13HSD17B10 | |
| SCHEMBL29125929 | 0.68 | TSHR (0.48) | TSHRLMNAKMT2AMMP13HSD17B10 | |
| SCHEMBL29125947 | 0.68 | TSHR (0.40) | TSHRLMNAKMT2AMMP13HSD17B10 | |
| SCHEMBL29125737 | 0.68 | TSHR (0.41) | TSHRLMNAKMT2AMMP13HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247361-A | Phenol-oxazolone/thioketone compound and synthetic method and application thereof | 吉首大学 | 2023-12-19 | — | — | CN | disclosed |