SCHEMBL29129191

SCHEMBL29129191

N[C@@H](CCCCNC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.57
MDM4 O15151 1/20 0.44
TP53 P04637 1/20 0.44
CASP3 P42574 2/20 0.43
ANPEP P15144 1/20 0.43
TLR2 O60603 3/20 0.42
MDM2 Q00987 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29129196 1.00 KMT2A (0.57) KMT2AMDM4TP53CASP3ANPEP
SCHEMBL29613497 0.91 KMT2A (0.53) KMT2ACASP3ANPEPTLR2MDM2
SCHEMBL29681768 0.91 KMT2A (0.55) KMT2ATLR2MDM2
SCHEMBL29613477 0.90 KMT2A (0.52) KMT2AANPEP
SCHEMBL29129039 0.90 KMT2A (0.52) KMT2ATLR2MDM2
SCHEMBL29129046 0.90 KMT2A (0.52) KMT2ATLR2MDM2
SCHEMBL23286117 0.87 KMT2A (0.55) KMT2ATLR2MDM2
SCHEMBL2089280 0.87 KMT2A (0.67) KMT2AMDM4TP53CASP3ANPEP
SCHEMBL10052316 0.87 KMT2A (0.67) KMT2AMDM4TP53CASP3ANPEP
SCHEMBL29398504 0.87 KMT2A (0.67) KMT2AMDM4TP53CASP3ANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117279636-A Methods and compounds for modulating myotonic muscular dystrophy type 1 设计治疗公司 2023-12-22 CN disclosed