Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 13/20 | 0.81 |
| ▸ | PFKFB3 | Q16875 | 4/20 | 0.53 |
| ▸ | PFKFB4 | Q16877 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2905833 | 0.90 | CMA1 (1.00) | CMA1PFKFB3PFKFB4L3MBTL1NPSR1 | |
| SCHEMBL2912893 | 0.90 | CMA1 (0.82) | CMA1PFKFB3PFKFB4L3MBTL1NPSR1 | |
| SCHEMBL2910756 | 0.90 | CMA1 (0.85) | CMA1PFKFB3PFKFB4 | |
| SCHEMBL2910824 | 0.88 | CMA1 (0.81) | CMA1PFKFB3PFKFB4 | |
| SCHEMBL2912236 | 0.81 | CMA1 (0.82) | CMA1PFKFB3PFKFB4L3MBTL1NPSR1 | |
| SCHEMBL2910110 | 0.81 | CMA1 (1.00) | CMA1PFKFB3PFKFB4 | |
| SCHEMBL2913594 | 0.81 | CMA1 (0.66) | CMA1PFKFB3PFKFB4L3MBTL1NPSR1 | |
| SCHEMBL13572241 | 0.81 | CMA1 (0.71) | CMA1PFKFB3PFKFB4 | |
| SCHEMBL2908164 | 0.80 | CMA1 (0.76) | CMA1PFKFB3PFKFB4L3MBTL1NPSR1 | |
| SCHEMBL16775639 | 0.80 | CMA1 (0.67) | CMA1PFKFB3PFKFB4L3MBTL1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1325920-B1 | N-SUBSTITUTED BENZOTHIOPHENESULFONAMIDE DERIVATIVES | TOA EIYO LTD (JP) | 2010-08-25 | — | — | EP | claimed |
| EP-1666067-A1 | DRUG CONTAINING CHYMASE INHIBITOR AS THE ACTIVE INGREDIENT | Teijin Pharma Limited (JP) | 2006-06-07 | — | — | EP | disclosed |