Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | APLNR | P35414 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29129581 | 1.00 | GAA (0.58) | GAAHPGDALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL5281585 | 1.00 | GAA (0.58) | GAAHPGDALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL29129524 | 1.00 | GAA (0.58) | GAAHPGDALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL3916388 | 1.00 | GAA (0.58) | GAAHPGDALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL21588244 | 0.98 | GAA (0.55) | GAAHPGDALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL21389843 | 0.95 | BTK (0.53) | GAAHPGDALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL6027856 | 0.91 | GAA (0.50) | GAAHPGDALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL15026749 | 0.84 | GAA (0.45) | GAASMN1; SMN2HSD17B10BTKHTT | |
| SCHEMBL29026542 | 0.84 | BTK (0.49) | GAAHPGDALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL440267 | 0.83 | GAA (0.44) | GAAALDH1A1SMN1; SMN2HSD17B10BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247338-A | N-amino-alpha-amino acid compound and synthesis method thereof | 四川大学 | 2023-12-19 | — | — | CN | disclosed |