SCHEMBL29129649

SCHEMBL29129649

FC(F)C(F)(Br)c1ccc(Br)c(C(F)(F)F)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.43
NPSR1 Q6W5P4 2/20 0.43
XBP1 P17861 1/20 0.43
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
LMNA P02545 2/20 0.40
NOTUM Q6P988 3/20 0.38
HTT P42858 2/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
CES2 O00748 2/20 0.35
EPHX1 P07099 2/20 0.35
TAS2R14 Q9NYV8 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
PDE3B Q13370 1/20 0.33
PDE3A Q14432 1/20 0.33
ALKBH5 Q6P6C2 1/20 0.33
TMPRSS4 Q9NRS4 1/20 0.32
IDO1 P14902 1/20 0.32
AR P10275 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29632676 0.81 MAPT (0.53) MAPTNPSR1XBP1MEN1KMT2A
SCHEMBL496276 0.81 MAPT (0.53) MAPTNPSR1XBP1MEN1KMT2A
SCHEMBL10183548 0.76 MAPT (0.45) MAPTNPSR1XBP1MEN1KMT2A
SCHEMBL24244877 0.76 MAPT (0.45) MAPTNPSR1XBP1MEN1KMT2A
SCHEMBL10871860 0.76 MAPT (0.45) MAPTNPSR1XBP1MEN1KMT2A
SCHEMBL29129641 0.76 PDE2A (0.41) NOTUMCES2IDO1
SCHEMBL17711271 0.73 AR (0.59) MAPTNPSR1XBP1MEN1KMT2A
SCHEMBL29509444 0.73 AR (0.59) MAPTNPSR1XBP1MEN1KMT2A
SCHEMBL20919102 0.73 MAPT (0.43) MAPTNPSR1XBP1MEN1KMT2A
SCHEMBL29129628 0.73 TSHR (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110505874-B Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2023-09-26 CN disclosed