Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1576896 | 0.84 | EPHX2 (0.97) | EPHX2ALDH1A1CYP3A4CYP2C19MEN1 | |
| SCHEMBL12931880 | 0.82 | EPHX2 (1.00) | EPHX2ALDH1A1 | |
| SCHEMBL19966024 | 0.82 | EPHX2 (0.77) | EPHX2ALDH1A1CYP3A4CYP2C19MEN1 | |
| SCHEMBL30272384 | 0.81 | EPHX2 (0.66) | EPHX2ALDH1A1CYP3A4CYP2C19MEN1 | |
| SCHEMBL30272383 | 0.81 | EPHX2 (0.66) | EPHX2ALDH1A1CYP3A4CYP2C19MEN1 | |
| SCHEMBL31321450 | 0.80 | EPHX2 (0.77) | EPHX2ALDH1A1 | |
| SCHEMBL12931878 | 0.78 | EPHX2 (1.00) | EPHX2ALDH1A1 | |
| SCHEMBL31529425 | 0.77 | EPHX2 (0.69) | EPHX2ALDH1A1CYP3A4CYP2C19MEN1 | |
| SCHEMBL31174537 | 0.76 | EPHX2 (0.68) | EPHX2ALDH1A1CYP3A4CYP2C19MEN1 | |
| SCHEMBL31276295 | 0.76 | EPHX2 (0.72) | EPHX2ALDH1A1CYP3A4CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117069698-A | Double-functional molecule targeting SHP2 degradation and preparation and application thereof | 苏州大学 | 2023-11-17 | — | — | CN | disclosed |