Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29059253 | 1.00 | CYP2D6 (0.32) | CYP2D6CYP2C19PIK3CDMMP8TSHR | |
| SCHEMBL15562350 | 1.00 | CYP2D6 (0.32) | CYP2D6CYP2C19PIK3CDMMP8TSHR | |
| SCHEMBL28908979 | 0.82 | CYP2D6 (0.31) | CYP2D6CYP2C19 | |
| SCHEMBL23168321 | 0.80 | CYP2C19 (0.41) | CYP2D6CYP2C19PIK3CDMMP8 | |
| SCHEMBL28596003 | 0.80 | CYP2D6 (0.30) | CYP2D6CYP2C19 | |
| SCHEMBL28591507 | 0.80 | — | — | |
| SCHEMBL19946151 | 0.77 | CA1 (0.41) | CYP2D6 | |
| SCHEMBL15269338 | 0.77 | CA1 (0.41) | CYP2D6 | |
| SCHEMBL2447756 | 0.77 | — | — | |
| SCHEMBL28597589 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117295736-A | Benzo [ C ] [2,6] naphthyridine derivatives, compositions thereof and therapeutic uses thereof | 剑桥实业有限公司 | 2023-12-26 | — | — | CN | disclosed |